Efficacy of Ipratropium Bromide in Acute Childhood Asthma: A Meta-analysis

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Efficacy of ipratropium bromide in acute childhood asthma: a meta-analysis.

PURPOSE To determine whether inhaled ipratropium bromide provides an additive, clinically important improvement in children with acute asthma who are being treated with beta 2-agonists. METHODS An English-language literature search was conducted employing MEDLINE (1966 to 1992), Science Citation Index (1986 to 1992) using key citations, bibliographic reviews of primary research and review art...

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A meta-analysis of the effects of ipratropium bromide in adults with acute asthma.

PURPOSE To review the literature to determine whether inhaled ipratropium bromide provides additive benefits to adults with acute asthma who are being treated with beta-agonists in an emergency department. SUBJECTS AND METHODS English-language studies, both published (1978 to 1999) and unpublished, were retrieved using Medline, Science Citation Index, Current Contents, bibliographic reviews o...

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Ipratropium bromide in children with asthma.

Eighteen children between 6 and 14 years of age with perennial asthma were studied over two four-week treatment periods. Ipratropium bromide, given in addition to their current treatment, was compared with placebo using a double-blind crossover technique. The period of treatment with ipratropium was associated with a significant reduction in symptoms during both day and night and significantly ...

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Ineffectiveness of ipratropium bromide in acute bronchiolitis.

In a double blind randomised trial, we found no evidence that nebulised ipratropium bromide was of clinical benefit in acute bronchiolitis.

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Ipratropium bromide: a review of its pharmacological properties and therapeutic efficacy in asthma and chronic bronchitis.

Ipratropium bromide is an anticholinergc bronchodilator administered by inhalation. Although producing bronchodilation in most patients with obstructive airways disease, it is somewhat less effective than beta 2-adrenoceptor agonist drugs such as salbutamol or fenoterol in patients with asthma, but is at least as effective as these agents in bronchitis. As with the beta 2-adrenoceptor agonists,...

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ژورنال

عنوان ژورنال: Academic Emergency Medicine

سال: 1995

ISSN: 1069-6563,1553-2712

DOI: 10.1111/j.1553-2712.1995.tb03607.x